Building Bridges between Biotechnology and Chemistry – Oreste Ghisalba's Pioneering Activities, Publications and Programs

Building and breaking bridges between sister chromatids.

Eukaryotic chromosomes undergo dramatic changes and movements during mitosis. These include the individualization and compaction of the two copies of replicated chromosomes (the sister chromatids) and their subsequent segregation to the daughter cells. Two multisubunit protein complexes termed 'cohesin' and 'condensin', both composed of SMC (Structural Maintenance of Chromosomes) and kleisin su...

Building Bridges between Research and Applications

IEEE Computer Graphics and Applications magazine was launched in 1980, when I was in third grade on the other side of the Iron Curtain. In its first issue, then Editor in Chief Michael J. Wozny talked about the growing importance of computer graphics and applications in industry and science. This magazine “will appeal to the end user as well as to the specialist. Each issue will cover a broad s...

Building Bridges Between Convex Regions

In the Euclidean traveling salesman and buyers problem (TSBP), we are given a set of convex regions in d-dimensional space, and we wish to nd a minimum-cost tour that visits all the regions. The cost of a tour depends on the length of the tour itself and on the distance that buyers within each region need to travel to meet the salesman. We show that constantfactor approximations to the TSBP and...

Building Bridges between Neural Models

Biotechnology and Green Chemistry

White biotechnology can be regarded as applied biocatalysis, with enzymes and microorganisms, aiming at industrial production of bulk and fine chemicals to food and animal feed additives. In its turn biocatalysis has many attractive features in the context of greenchemistry: mild reaction conditions (physiological pH and temperature); environmentally compatible catalysts and solvent (often wate...